Digital Pathology Blog

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Posted by David C. Wilbur, M.D. 03/12/2024

Transforming Clinical Workflow: Digital Pathology in Research and Education

Digital pathology offers significant advantages to pathology laboratories within academic institutions. In addition to clinical activities, for which digital pathology has already shown significant improvements in workflow efficiency and accuracy, such laboratories have missions of research and education, both of which can also be enhanced in the digital environment.

Case-based research projects and educational activities require the use of whole slide images (WSIs) derived from the clinical workflow. But cases flowing into these activities have specific requirements and workflows of their own.

Topics: Digital Pathology, Electronic Health Records, Pathology, Artificial Intelligence

Posted by Robin Weisburger 08/08/2023

International Color Consortium: Enhancing Color Accuracy and Consistency for Your Digital Pathology Images

The ICC Profile: What Is It and Why Is It Important When Considering Digital Pathology Technologies?

Consistency and reliability of image quality is more important than ever as the adoption of digital pathology increases across clinical, education and research workflows.

The International Color Consortium (ICC) has developed a set of standards to be applied in the management of color for digital images. In color management, the ICC profile is a set of data that characterizes a color input or output device or a color space according to standards promulgated by the Consortium.

Topics: Digital Pathology, Pathology, Slide Management

Posted by Robin Weisburger 03/07/2023

Digital Pathology Communication without the Keyboard – Real-time Voice Becomes an Option

Anatomic Pathology has been experiencing a major paradigm shift over the past several years as digital technology provides new ways of performing the daily work. Changes in workflow are affecting all aspects of pathology, whether clinical, research or education.

The early years of whole-slide-scanning offered academic institutions a way to provide teaching sets, resident collections and publication images without requiring technical staff to perform additional recuts, staining procedures and handling of blocks and slides. While there was indeed clinical utilization of telepathology techniques as far back as 19681, widespread use was limited. Over time, however, the use of telepathology became a way to perform intra-operative consultations, share cases, collaborate and seek clinical opinions from colleagues and outside experts.

Topics: Digital Pathology, Telemedicine, Pathology, digital imaging, Telepathology

Posted by Keith Kaplan, MD, Chief Medical Officer 01/03/2023

What Will Our Legacy Be?

My maternal grandfather was a glazier. He was orphaned at a young age and raised in an orphanage on the West side of Chicago with 2 brothers. One of those brothers died during adolescence. My grandfather and his oldest brother fought in World War II and became part of America’s Greatest Generation. He and his brother started Chicago Glass which became the largest glazier company in the city. For over 30 years, my grandfather hung glass on some of the tallest buildings in the world at the time. Sears Tower, John Hancock, Lake Point Tower, Standard Oil, you name it, he worked on it. Buildings downtown had to be “glassed in” by November 15 if the electricians, plumbers, elevator, drywall and carpet guys were to have a chance to work through the winter for spring occupancy on a residential or commercial high rise. In the winters, my grandfather drove a cab between “indoor” jobs such as hanging mirrors, repairing windows or building storm windows. He would drive me around in his large Checker cab and point out what buildings he worked on and what he did, what worked and what didn’t, if he got injured, or one of his men did, and when they “glassed” it in.

Topics: Digital Pathology, Healthcare, Pathology, Management

Posted by David C. Wilbur, M.D. 11/30/2022

Image Management in Research: Use Cases and Workflow Solutions

We were privileged to present at the Digital Pathology and AI forum hosted by The Pathologist. In our portion of the forum, Dr. Wilbur focused on how the use cases and workflow solutions of digital pathology compare to those in the clinical environment. Dr. Wilbur focuses on how the use cases and workflow solutions of digital pathology compare to those in the clinical environment. While both of these are well established in the clinical setting, image management systems need some additional features to satisfy the requirements for research. Use cases and workflows are similar in how the user interacts with the digital environment but can be quite different in how they relate to the ultimate task and output.

Topics: Digital Pathology, Pathology, Artificial Intelligence

Posted by Robin Weisburger 06/21/2022

Digital Solutions for Training Today's Pathologists

The strains of the last two plus years have forced us to make many changes to our daily routines, both on a personal and a professional level. Remote interactions have become the norm, with families “zooming” for the holidays and family events, elbow bumps instead of hand-shakes, and remote work conferences and meetings in all walks of life. We are all looking forward to the return to many of our previous lifestyles, but the old adage remains true, out of adversity comes opportunity.

Topics: Digital Pathology, Pathology, digital imaging

Posted by Keith Kaplan, MD, Chief Medical Officer 05/10/2022

The Tumor Board, Virtually

There is a joke among surgeons and oncologists -- the pathologist at a tumor board is like the guy whose funeral that you are attending; you can't do it without him, but you don't want him saying too much. 

Nearly 2 years ago, our tumor boards went "virtual". Like billions around the world, we scrambled to get Zoom, GoToMeeting, WebEx and other applications up and running to hear each other’s voices and share screens to show radiology and pathology images. We anticipated that by the Summer or Fall we would be back to "normal".

Topics: Digital Pathology, Healthcare, Studies/Reports, Telemedicine, Pathology

Posted by David C. Wilbur, M.D. 04/05/2022

Proficiency Testing in the Digital Pathology Age

Don’t get me wrong based on the title; I am not advocating for proficiency testing (PT). After Medical Boards, Resident In-Service and Board exams, I never thought I would be thinking about any more testing at all. There are better ways to test for ongoing real proficiency. Exercises that test “real-world” skills, such as focused review of signed out cases or concurrent reviews - with feedback – not only lead to better outcomes (patient safety) but also improve practice (constructive feedback). But testing is an unfortunate part of modern life. It’s a metric, and regulators like metrics. For years we dealt with the specter of impending gynecologic cytology PT. Based on the complexity of the federally mandated glass slide testing format, the organizations capable of producing such a monumental effort appeared to reach a détente with CMS, and no testing took place for many years after the federal regulation went into effect. However, when one organization came up with a program, the seeming détente was at an end, and CAP and ASCP were essentially forced to enter the fray.

Topics: Digital Pathology, Pathology, digital imaging, Slide Management

Posted by Keith Kaplan, MD, Chief Medical Officer 11/02/2021

What Does the Gene Panel Show?

Recently I received a call from an oncologist. After giving me the patient’s name, she asked “What does the gene panel show?”

I responded we didn’t have the patient’s biopsy yet, that he was scheduled to undergo a CT-guided needle core biopsy, and we would process it overnight and review tomorrow as we normally do.

The oncologist acknowledged the patient was undergoing the biopsy in the afternoon, and we hadn’t even yet done an immediate fine needle aspiration rapid on-site assessment prior to the core biopsy.

Topics: Digital Pathology, Healthcare, Pathology

Posted by Keith Kaplan, MD, Chief Medical Officer 11/17/2020

The Paraffin Curtain is Melting

Surgical pathology is increasingly becoming more based in molecular diagnoses rather than morphologic diagnoses. For 150 years, morphology has been an accurate predictor of clinical behavior with standardized criteria for both histological grading and pathologic staging of tumors. While there are certainly “gray areas” in morphology and classification of disease, a traditional approach of classifying tumors based on location, gross pathologic findings and histologic findings combined with immunohistochemistry, over the past 30 years, has served our patients well in terms of classifying tumors for appropriate therapy and management.

Topics: Pathology